Nevertheless, the expression of FNDC5 in human subcutaneous WAT can be 100 folds less than that in skeletal muscle (41). receptors cooperate for the gene promoter to induce its transcription. We discovered that FNDC5/irisin stimulates the runt-related transcriptional elements RUNX1/2 a focal adhesion kinaseCdependent pathway in both bone tissue and subcutaneous white adipose cells. Mechanistically, […]