Regular dosing and emapalumab dose adaptation were utilized to take into account highly adjustable IFN levels and potential target\mediated drug disposition. Results Great inter\ and intra\specific variability in IFN production (assessed simply by total IFN levels, range: 102\106?pg/mL) was seen in pHLH sufferers. sufferers with HLH implemented emapalumab in research NI\0501\04/?05 or for compassionate use […]