HER3 belongs to the type I transmembrane tyrosine kinase family of receptors and activates intracellular signaling pathways, mainly the PI3K/AKT and MAPK/ERK pathways, upon dimerization with other HER family members (2, 5). the mRNA-based ERBB3 expression by central assessment. The primary endpoint is a CelTIL score after one single dose. A translational research plan is […]